Cisplatin macrophage

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August undefined, 2024

WebMar 10, 2024 · Original research: CircITGB6 promotes ovarian cancer cisplatin resistance by resetting tumor-associated macrophage polarization toward the M2 phenotype - PMC Back to Top Skip to main content An official website of the United States government Here's how you know The .gov means it’s official. WebOct 3, 2024 · Macrophage migration inhibitory factor (MIF) is elevated in patients with acute kidney injury (AKI) and is suggested as a potential predictor for renal replacement therapy in AKI. In this study, we found that MIF also plays a pathogenic role and is a therapeutic target for AKI. In a cisplatin-induce …

Cisplatin Uptake in Macrophage Subtypes at the Single …

WebJun 11, 2024 · VNS treatment significantly suppressed cisplatin-induced kidney injury. This effect was abolished by splenectomy, while adoptive transfer of GTS-21-treated … WebApr 13, 2024 · Background. Cisplatin-based chemotherapy is frequently used to treat advanced gastric cancer (GC). However, the resistance often occurs with the … reading comprehension k 10 reader

Blocking Macrophage Migration Inhibitory Factor Protects …

WebNov 30, 2024 · For the first time, in vitro studies on cisplatin exposure addressed human monocytes and monocyte-derived macrophages (undifferentiated THP-1 monocytic … WebCisplatin decreases mitochondrial function in sensory axons, and HDAC6 inhibition can promote axonal transport of healthy mitochondria. Indeed, the HDAC6 inhibitor normalized cisplatin-induced tibial nerve mitochondrial deficits. However, this was independent of macrophages and IL-10 signaling. WebApr 1, 2016 · Cisplatin is currently one of the most effective chemotherapeutic drugs used for treating ovarian cancer; however, resistance to cisplatin is common. In this study, we explored an experimental strategy for overcoming cisplatin resistance of human ovarian cancer from the new perspective of cancer cell metabolism. reading comprehension kindergarten free pdf

Resveratrol enhanced chemosensitivity by reversing macrophage ...

WebMar 1, 2024 · Here, we demonstrated that cisplatin-stimulated classically activated macrophages (CAMs) promote ovarian cancer cell migration by increasing CCL20 production, which activates its receptor CCR6 on ovarian cancer cells, triggering … WebAug 24, 2024 · 1. Introduction. Cisplatin (CDDP), a platinum-based anticancer agent, is one of the most commonly used chemotherapy drugs in the treatment of patients with various types of cancer, such as bladder, ovarian, head and neck, lung, testicular, cervical, esophageal, and breast cancer [].CDDP and its analogs, carboplatin and oxaliplatin, … how to stringify json object in lwcWebNational Center for Biotechnology Information how to strip a dog

"WebIndependent of platinum resistance status, ovarian cancer cells polarize macrophages toward M2-like type, whereas macrophages induce epithelial-mesenchymal transition and stemness-related gene expression profile in cisplatin-sensitive, but … " - Cisplatin macrophage

Cisplatin macrophage

Cell pyroptosis in health and inflammatory diseases

WebApr 11, 2024 · 2024年查处的不端行为案件处理结果通报（第一批次）. 近期，经国家自然科学基金委员会监督委员会调查审议、国家自然科学基金委员会委务会议审定，国家自然科学基金委员会对相关科研不端案件涉事主体进行了处理。. 现将给予通报批评的有关案情及处理 ...

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WebDec 2, 2024 · The use of resveratrol with cisplatin inhibited suppressed tumor growth when compared with cisplatin alone. Conclusion This study revealed that resveratrol inhibited breast cancer cell proliferation by promoting M1/M2 macrophage polarization ratio and suppressing IL-6/pSTAT3 pathway. Introduction WebM2 macrophage polarization modulates epithelial-mesenchymal transition in cisplatin-induced tubulointerstitial fibrosis Biomedicine (Taipei). 2016 Mar;6 (1):5. doi: 10.7603/s40681-016-0005-5. Epub 2016 Feb 10. Authors Chia-Cherng Yu 1 2 , Chiang-Ting Chien 3 , Tzu-Ching Chang 4 5 Affiliations

WebSep 13, 2024 · Our findings in cisplatin-induced injury underscore the value of dissecting the functions of individual MP subsets in kidney disease, which may enable therapeutic targeting of specific immune components in the absence of general immunosuppression. Sign up for PNAS alerts. Get alerts for new articles, or get an alert when an article is cited. WebJan 24, 2024 · The results suggested that SQFZ could inhibit MDA-MB-231/DDP cell growth related to M2 macrophages. When cisplatin was used in combination with SQFZ 40 …

WebCisplatin (DDP) is a common therapeutic option for non-small cell lung carcinoma (NSCLC). However, some patients fail to respond to the DDP chemotherapy. Therefore, identifying novel biomarkers to improve the diagnosis and treatment of NSCLC is important. Ubiquitin-specific protease (USP14) is involved in various pathological conditions ... WebApr 13, 2024 · Background: Cisplatin-based chemotherapy is frequently used to treat advanced gastric cancer (GC). However, the resistance often occurs with the mechanisms being not well understood. Recently, emerging evidence indicates that tumor-associated macrophages (TAMs) play an important role in chemoresistance of cancer.

WebFor the first time, in vitro studies on cisplatin exposure addressed human monocytes and monocyte-derived macrophages (undifferentiated THP-1 monocytic cells, differentiated …

WebIn IL-4-activated macrophages (M2 macrophages), the Krebs cycle and oxidative phosphorylation are intact and fatty acid oxidation (FAO) is also utilized. These metabolic alterations in response to the nature of the stimulus are proving to be determinants of the effector functions of M1 and M2 macrophages. reading comprehension klasse 9 gymnasiumWebNov 1, 2014 · Cisplatin, a member of platinum agents, is one of the most widely used anticancer chemical drugs and a part of the treatment to many types of solid tumors, including head and neck, breast, testicular, ovarian, cervical, lung, and colorectal cancers (Rabik & Dolan, 2007 ). how to strip a carWebMar 18, 2024 · Salvagno et al. 4 found that neutrophils, but not macrophages, limit tumour response to cisplatin by suppressing CD8 + … how to strip a blackstone griddleWebNov 1, 2014 · Low dose cisplatin exhibits therapeutic effects on CLP induced polymicrobial sepsis potentially by promoting macrophage phenotype to M1, expanding macrophage … how to strip a 1911 pistolWebMethods: We developed and compared different methods of loading exosomes released by mononuclear M1 and M2 macrophages from umbilical cord blood with cisplatin. We characterized the morphology, drug capacity, method of cellular entry, and antitumor efficacy of the exosomes in vitro. how to strip a permWebNational Center for Biotechnology Information how to strip a brass bedWebMacrophage Stimulating Protein May Promote Tubular Regeneration after Acute Injury . × Close Log In. Log in with Facebook Log in with Google. or. Email. Password. Remember me on this computer. or reset password. Enter the email address you signed up with and we'll email you a reset link. ... how to strip a bed nursing