Web1 jul. 2024 · Chi, Hongbo / St. Jude Children's Research Hospital Publications Shi, Hao; Liu, Chaohong; Tan, Haiyan et al. (2024) Hippo Kinases Mst1 and Mst2 Sense and Amplify IL-2R-STAT5 Signaling in Regulatory T Cells to Establish Stable Regulatory Activity. WebYAP is a transcriptional coactivator of the Hippo signaling pathway that has largely been studied for its role in the regulation of organ size during development. Several studies have shown that YAP is upregulated in cancer cells, and more recently in the T regulatory (Treg) subset of CD4+ cells. These observations suggest that the transcriptional co-activator …
Yu Lab St. Jude Research
Web24 feb. 2024 · Memphis, Tennessee, February 24, 2024 First author Seon Ah Lim, Ph.D., and corresponding author Hongbo Chi, Ph.D., both of St. Jude Immunology, contributed to research that raises the potential for … Web15 jan. 2024 · In this study, we have demonstrated that graded DGK activities differentially control CD4 + T H differentiation. Although, the absence of either DGKα or ζ selectively impairs T H 1 differentiation, simultaneous ablation of both DGKα and ζ enhances both T H 1 and T H 17 responses in vitro and in vivo. eia shale basins
Study reveals metabolic pathways that influence immune cells
Web21 mrt. 2024 · Oxygen levels vary between 0 and 19% in healthy mammalian tissues. The tissues closest to atmospheric oxygen levels (21.1% or 160 mmHg at sea level) are those of the upper airways (approximately 19%, 150 mmHg) ( 2 ). Lymphoid tissues are lower in oxygen; bone marrow is approximately 6.4% (50 mmHg) ( 2) and the spleen can range … Web17 mrt. 2024 · Hongbo Chi,教授. St. Jude儿童研究医院教授;Robert G. Webster免疫系荣誉主席. 刘小龙,研究员. 中国科学院上海细胞与生化所所长. 宁光,教授. 中国工程院院士;瑞金医院副院长. 韩家淮,教授. 中国科学院院士;厦门大学副校长. 苏冰,教授. 上海市免 … Web16 nov. 2024 · St. Jude researchers on the 2024 list of Highly Cited Researchers and the scientific fields in which they are highly cited are: Kelly Caudle, Pharm.D., Ph.D., Pharmaceutical Sciences (Pharmacology ... eia shopping