Irf2bp1

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August undefined, 2024

WebIRF2BP1 also acts as a transcriptional corepressor in a IRF2-dependent manner. This repression is not med... Retrieving Each-+ Anti-HS1BP3 Rabbit Polyclonal Antibody (Alexa Fluor® 647) Catalog Number: (10263-710) Supplier: Bioss. … WebSequence variants and/or copy number variants (deletions/duplications) within the IRF2BP1 gene will be detected with >99% sensitivity. Variants classified as unknown significance (VUS), likely pathogenic, or pathogenic will be reported. Benign and likely benign variants are generally not reported.

IRF2BP1 Gene - GeneCards I2BP1 Protein I2BP1 Antibody

WebCompared across the COVID-19 disease spectrum, we found type I interferon (IFN) responses to be significantly upregulated (IFNAR2, IRF2BP1, IRF4, MAVS, SAMHD1, TRIM1), or downregulated (SOCS3, IRF2BP2, IRF2BPL) in Asymptomatic as compared with mild and severe COVID-19, with the dysregulation of an increasing number of ISGs associated with ... WebJan 22, 2024 · IRF2BP1, IRF2BP2, and IRF2BP1 + IRF2BP2 were knocked down in HeLa cells for 72 h, and gene expression data were recorded by microarray analysis; non-targeting siRNAs were used as a control. IRF2BP1 and IRF2BP2 have distinct and overlapping functions. Experiments were done in triplicates. GSEA of the highly significant enriched … onward rhymes

IRF-2BP1 Antibody (D-5) SCBT - Santa Cruz Biotechnology

WebNX_Q8IU81 - IRF2BP1 - Interferon regulatory factor 2-binding protein 1 - Function. Acts as a transcriptional corepressor in a IRF2-dependent manner; this repression is not mediated by histone deacetylase activities. May act as an E3 ligase towards JDP2, enhancing its polyubiquitination. Represses ATF2-dependent transcriptional activation. WebIrf2bp1: 272359: 7 A3: NM_178757: Q8R3Y8: N/A: Download Datasheet. Protocols Online. What application is the blocking peptide sc-373899 P appropriate for? Asked by: Cweed. Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. WebAll lanes : Anti-IRF2BP1 antibody [OTI3A6] (ab236392) at 1/2000 dilution Lane 1 : HEK-293T (human epithelial cell line from embryonic kidney transformed with large T antigen) cell lysates transfected with pCMV6-ENTRY control cDNA for 48 hrs Lane 2 : HEK-293T cell lysates transfected with pCMV6-ENTRY IRF2BP1 cDNA for 48 hrs Lysates/proteins at 5 … onward road

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Transient deSUMOylation of IRF2BP proteins controls early

WebIrf2bp1 Gene, Drug Resistance, Tissue Distribution, Mutation Distribution, Variants, Irf2bp1 Genome Browser, Irf2bp1 References. Irf2bp1 - Explore an overview of Irf2bp1, with a histogram displaying coding mutations, full tabulated details of all associated variants, tissue distribution and any drug resistance data. WebIRF2BP1 - interferon regulatory factor 2 binding protein 1 Gene. Gene. Protein. Ortholog. Homo sapiens. Gene ID: 26145 Gene type: protein coding. About IRF2BP1. Cytogenetic location: 19q13.32 Genomic coordinates (GRCh38): This gene has 1 transcript (splice variant), 225 orthologues and 5 paralogues. onward rightmoveWebOct 26, 2024 · We find that IRF2BP1 is a SUMO-dependent repressor, whose transient deSUMOylation on the DUSP1 promotor allows - and whose timely reSUMOylation restricts - DUSP1 expression. Our work thus provides a paradigm how comparative SUMO proteome analyses serve to reveal novel regulators in signal transduction and transcription. iot microsoft blog

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Irf2bp1

Web新用户请 ; 欢迎您光临佑研匠簇网上商城 Webirf2bp1 ID ZDB-GENE-050420-389 Name interferon regulatory factor 2 binding protein 1 Symbol irf2bp1 Nomenclature History Previous Names. si:dkey-223n17.3; Type protein_coding_gene

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WebMar 21, 2024 · GeneCards Summary for IRF2BP2 Gene. IRF2BP2 (Interferon Regulatory Factor 2 Binding Protein 2) is a Protein Coding gene. Diseases associated with IRF2BP2 include Immunodeficiency, Common Variable, 14 and Common Variable Immunodeficiency . An important paralog of this gene is IRF2BPL. Web13698-1-AP targets IRF2BP1 in WB, IP, IHC, IF, ChIP,ELISA applications and shows reactivity with human, mouse, rat samples. PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for …

WebJul 30, 2024 · Among the identified proteins, IRF2 Binding Protein 2 (IRF2BP2) was chosen for further analysis because of its uncharacterized function in transcriptional regulation of HNF4α. IRF2BP2 belongs to the IRF2BP protein family, which comprises IRF2BP1, IRF2BP2 and EAP1 (IRF2BPL) [19, 26, 27]. Webinterferon regulatory factor 2 binding protein 1. Overview. Perturbation Effects. Characterization. Description. Loading...

WebNov 1, 2014 · IRF2BP1. LOCATION. 19q13.32. LOCUSID. 26145. ALIAS-Non-annotated gene. Preliminary data : if you are an author who wish to write a full paper/card on this gene, contribute in submission tool. Other Information Locus ID: NCBI: 26145 MIM: 615331 HGNC: 21728 Ensembl: ENSG00000170604. Variants: WebIRF2BP1 - interferon regulatory factor 2 binding... Homo sapiens Synonyms: DKFZP434M154, IRF-2-binding protein 1, IRF-2BP1, Interferon regulatory factor 2-binding protein 1

WebMar 21, 2024 · IRF2BP1 (Interferon Regulatory Factor 2 Binding Protein 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include ligase activity. An important paralog of this gene is IRF2BPL. UniProtKB/Swiss …

WebAvantor ®, a Fortune 500 company, is a leading global provider of mission-critical products and services to customers in the biopharma, healthcare, education & government, and advanced technologies & applied materials industries.Our portfolio is used in virtually every stage of the most important research, development and production activities in the … onward ripoffWebWhilst the biological function of many lncRNAs remains unknown, recent evidence has suggested that lncRNAs may be important regulators of cellular growth, differentiation and may play a significant role in cancer. Epidermal growth factor (EGF) an activator of the ERK1/2 signalling cascade is an important spatio-temporal regulator of transcription and, … onward run coachingWebPrestige Antibodies ® are highly characterized and extensively validated antibodies with the added benefit of all available characterization data for each target being accessible via the Human Protein Atlas portal linked just below the product name at the top of this page. The uniqueness and low cross-reactivity of the Prestige Antibodies ® to other proteins are due … iot microsoft docWebMar 3, 2024 · Comparison of cells expressing wild type or SUMOylation-deficient IRF2BP1 indicates that transient deSUMOylation of IRF2BP proteins is important for appropriate expression of immediate early genes including dual specificity phosphatase 1 (DUSP1, MKP-1) and the transcription factor ATF3. We find that IRF2BP1 is a repressor, whose transient ... onward routingWebNX_Q8IU81 - IRF2BP1 - Interferon regulatory factor 2-binding protein 1 - Gh. Acts as a transcriptional corepressor in a IRF2-dependent manner; this repression is not mediated by histone deacetylase activities. May act as an E3 ligase towards JDP2, enhancing its polyubiquitination. Represses ATF2-dependent transcriptional activation. on ward routineWebIRF2BP1 Antibodies. Antibodies that detect IRF2BP1 can be used in several scientific applications, including Western Blot, Immunohistochemistry, Immunocytochemistry and Immunoprecipitation. These antibodies target IRF2BP1 in Human, Rat and Mouse samples. Our IRF2BP1 monoclonal and polyclonal antibodies are developed in Mouse, Rabbit, Goat … onward roleplaying gameWebOfficial gene symbol, which is typically a short form of the gene name, according to HGNC. IRF2BP1 (DKFZP434M154, IRF-2BP1) Protein classi. Assigned HPA protein class (es) for the encoded protein (s). Read more. Enzymes. Number of transcriptsi. Number of protein-coding transcripts from the gene as defined by Ensembl. 1. onward roadmap